ABSTRACT
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic remains a constant challenge for healthcare systems and affects the well-being of many individuals. The objective of the current study is to determine the parameters that can predict post COVID-19 sequale and incidence of post Covid sequale among Covid survivor's patients attending post covid outpatient clinic. Patients and methods: This was a case control study carried out on 60 COVID-19 survivors whom were recovered from the acute illness and discharged for follow-up at the post covid out-patient clinic at Zagazig University. The sixty patients included in the study were divided to Group I: (Asymptomatic patients): include 30 patients whom were discharged for follow-up and in whom no significant symptoms or signs were reported during the study. Group II: (Symptomatic patients): include 30 patients whom were discharged for follow-up and in whom there were significant symptoms or signs during the study. Results: There is statistically significantly association between initial parameters high (CRP, D-dimer, ferritin, LDH, IL6) and low Lymphocytes. Post covid degree of lung affection in chest CT scan where Grade ≥5 (severe lung affection) prevailed in 63.3% and 20% in those with and without post covid syndrome, respectively, while Grade <2 (less sever lung affection) was more dominant in those without post covid (30% vs. 6.7%). Conclusion: Persistence of symptoms is common after the acute phase of COVID-19 infection. Post covid syndrome occurs regardless of the disease severity. High CRP, LDH, ferritn, D-dimer, and IL6, low Lymphocytes and degree of lung affection at diagnosis of acute covid19 may be good predictors for the occurrence of post covid syndrome. © 2022, Ain Shams University Faculty of Medicine. All rights reserved.
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in global healthcare crises and strained health resources. As the population of patients recovering from COVID-19 grows, it is paramount to establish an understanding of the healthcare issues surrounding them. COVID-19 is now recognized as a multi-organ disease with a broad spectrum of manifestations. Similarly to post-acute viral syndromes described in survivors of other virulent coronavirus epidemics, there are increasing reports of persistent and prolonged effects after acute COVID-19. Patient advocacy groups, many members of which identify themselves as long haulers, have helped contribute to the recognition of post-acute COVID-19, a syndrome characterized by persistent symptoms and/or delayed or long-term complications beyond 4 weeks from the onset of symptoms. Here, we provide a comprehensive review of the current literature on post-acute COVID-19, its pathophysiology and its organ-specific sequelae. Finally, we discuss relevant considerations for the multidisciplinary care of COVID-19 survivors and propose a framework for the identification of those at high risk for post-acute COVID-19 and their coordinated management through dedicated COVID-19 clinics. Copyright © 2022, Anka Publishers. All rights reserved.